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Cat. Number
733979556437429
Chemical Name
5-Hydroxy Vioxx
CAS Number
185147-17-5
Category
Aromatics, Heterocycles, Metabolites & Impurities, Sulfur & Selenium Compounds
Mol. Formula
C17H14O5S
Mol. Weight
330.36
Qty 1
1mg
Qty 2
10mg
Application Notes
A metabolite of Vioxx. The biotransformation of Rofecoxib (Vioxx) was highly dependent on the subcellular fraction and the redox system used.
Synonym
5-Hydroxy-4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone; 5-Hydroxyrofecoxib;
References

Funaki, T., et al.: Biochem. Pharmacol., 38, 4213 (1989),
John, B., et al.: Xenobiotica, 22, 1339 (1992),
Jouzeau, J., et al.: Drugs, 53, 563 (1997),
Baillie, T., et al.: Drug Metab. Dispos., 29, 1614 (2001),

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