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Cat. Number
733979520177473
Chemical Name
(R)-(+)-5’-Hydroxyphenyl Carvedilol
Category
Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C24H26N2O5
Mol. Weight
422.47
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Powder
Application Notes
An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.
Synonym
(R)-3-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol; (R)-5-Hydroxycarvedilol; (R)-(+)-BM 140830; (R)-(+)-M4;
Melting Pt.
205-207°C
Solubility
Acetic Acid, DMF, DMSO
References

Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987),
Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990),
Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990),
Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),

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