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Cat. Number
733978663397573
Chemical Name
(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester
CAS Number
215917-99-0
Category
Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C10H19NO4
Mol. Weight
217.26
Qty 1
50mg
Qty 2
500mg
Application Notes
An intermediate of BMS-599626, a selective and orally efficacious inhibitor of human epidermal growth factor receptor 1 and 2 kinases.
Synonym
(3R)-3-(Hydroxymethyl)-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Ester; tert-Butyl (3R)-3-(Hydroxymethyl)morpholine-4-carboxylate; (R)-N-Boc-3-Hydroxymethylmorpholine;
References

Xia, W., et al.: Clin. Cancer Res., 5, 4164 (1999),
Hunt, J., et al.: J. Med .Chem., 47, 4054 (2004),
Baselga, J., et al.: J. Clin. Oncol., 23, 2445 (2005),
Fink, B., et al.: Bioorg. Med. Chem. Lett., 15, 4774 (2005),

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