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Cat. Number
733978497739007
Chemical Name
N-(2-Hydroxyethyl)-11-azaartemisinin
CAS Number
255731-00-1
Category
Chiral Reagents, Drug Analogues, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C17H27NO5
Mol. Weight
325.40
Qty 1
1mg
Qty 2
10mg
Application Notes
A derivative of 11-Azaartemisinin which showed a high order of activity against multidrug-resistant malaria by oral route.
Synonym
(3R,5aS,6R,8aS,9R,12R,12aR)-Decahydro-11-(2-hydroxyethyl)-3,6,9-trimethyl-3,12-epoxy-1,2-dioxepino[4,3-i]isoquinolin-10(3H)-one;
References

Meshnick, S.R., et al.: Microbiol. Rev., 60, 301 (1996),
O’Neill, P.M., et al.: J. Med. Chem., 45, 1052 (2002),
Rottmann, M., et al.: J. Med. Chem., 51, 1035 (2008),

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