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Cat. Number
733978559772101
Chemical Name
rac 8-Hydroxy Efavirenz-d4
Category
Isotope Labelled Compounds, Metabolites, Non-nucleoside Reverse Transcriptase, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C14H5D4ClF3NO3
Mol. Weight
335.70
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Solid
Application Notes
A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor.
Synonym
6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz;
Melting Pt.
144-154°C
Solubility
Ethyl Acetate, DMSO, Methanol
Storage condition
-20°C Freezer
References

Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994),
Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998),
Langmann, P., et al.: Eur. J. Med. Res., 7, 309(2002),
Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003),

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