6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

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Cat. Number	733978452617969
Chemical Name	6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
CAS Number	79952-42-4
Category	Chiral Reagents, Drug Analogues, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula	C19H28O4
Mol. Weight	320.42
Qty 1	10mg
Qty 2	100mg
Appearance	Off-White to Pale Yellow Solid
Application Notes	A Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.
Synonym	Lovastatin Diol Lactone; Antibiotic MB 530A; Lovastatin Diol Lactone; Monacolin J;
Melting Pt.	50-53°C
Solubility	Dichloromethane, DMF, DMSO, Ether, Ethyl Acetate, Methanol
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
References	Endo, A., et al.: J. Antibiot., 39, 1609 (1986), Aniya, Y., et al.: Gen. Pharmacol., 32, 225 (1999), Li, Y., et al.: J. Pharm. Biomed. Anal., 35, 1101 (2004), Akihisa, T., et al.: Chem. Biodivers, 2, 1305 (2005),
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