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Cat. Number
733978690432938
Chemical Name
4β-Hydroxy Cholesterol
CAS Number
17320-10-4
Category
Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol. Formula
C27H46O2
Mol. Weight
402.65
Qty 1
1mg
Qty 2
10mg
Application Notes
A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
Synonym
(3β,4β)-Cholest-5-ene-3,4-diol; Cholest-5-ene-3β,4β-diol; 3β,4β-Dihydroxycholest-5-ene; cis-3,4-Dihydroxy-5-cholestene; cis-5-Cholestene-3,4-diol;
References

Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995),
Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998),
Chawla, A., et al.: Science, 294, 1866 (2001),
Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),

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