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Cat. Number
733978663012599
Chemical Name
10-Hydroxy Camptothecin
CAS Number
19685-09-7
Category
Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C20H16N2O5
Mol. Weight
364.35
Qty 1
1mg
Qty 2
10mg
Appearance
Yellow Solid
Application Notes
A Camptothecin derivative; a topoisomerase inhibitor for cancer therapy.
Synonym
(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (S)-10-Hydroxycamptothecin; Hydroxycamptothecin; NSC 107124;
Melting Pt.
>250°C (dec.)
Solubility
Dimethylformamide, Dimethyl Sulfoxide
Storage condition
-20°C Freezer
References

Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986),
Miller, K.D., et al.: Invest. New Drugs, 22, 69 (2004),
Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (2004),
Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005),

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