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Cat. Number
733978572575149
Chemical Name
rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride
CAS Number
81408-49-3
Category
Inhibitors, Nucleotides, Bases & Related Reagents
Mol. Formula
C14H24ClN5O
Mol. Weight
313.83
Qty 1
50mg
Qty 2
500mg
Appearance
White to Off-White Solid
Application Notes
A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does ot inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM).
Synonym
EHNA
Melting Pt.
163-170°C
Solubility
DMSO, Water
Storage condition
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
References

Lorbar, M., et al.: J. Mol. Cell. Cardiol., 31, 401 (1999),
Verde, I., et al.: Br. J. Pharmacol., 127, 65 (1999),

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