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Cat. Number
733976393545633
Chemical Name
7-Ethyl-d3-camptothecin
Category
Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C22H17D3N2O4
Mol. Weight
379.42
Qty 1
1mg
Qty 2
10mg
Appearance
Beige Solid
Application Notes
An anticancer drug, showed strong activity against various murine tumors. A Labelled camptothecin(CPT) derivative as antineoplastic agent against drug-resistant tumors.
Synonym
(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-d3; 7-Ethyl-d3-20(S)-camptothecin; SN 22-d3
Solubility
N,N-Dimethylformamide, Dimethyl Sulfoxide
References

Miyake, K., et al.: Cancer Res., 59, 8 (1999),
Brangi, M., et al.: Cancer Res., 59 5938 (1999),
Bom, D., et al.: J. Med. Chem., 43, 3970 (2000),
Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).

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