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Cat. Number
733974159058832
Chemical Name
(S)-(-)-O-Desmethyl Carvedilol
CAS Number
123372-13-4
Category
Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C23H24N2O4
Mol. Weight
392.45
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Solid
Application Notes
An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity. [α]D= -18.7 (c= 0.1 methanol)
Synonym
(S)- 2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenol; (S)-(-)-O-Desmethylcarvedilol;
Melting Pt.
155-156°C
Solubility
Chloroform, Hot Methanol, Tetrahydrofuran
Storage condition
-20?C Freezer
References
Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),
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