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/ Products Classification 点击展开+| Cat. Number | 733974750816957 |
| Chemical Name | Desmethyl Bosentan |
| CAS Number | 253688-61-8 |
| Category | Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
| Mol. Formula | C26H27N5O6S |
| Mol. Weight | 537.59 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Appearance | Green-Yellowish Foamy Solid |
| Application Notes | A metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator. |
| Synonym | 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2’-bipyrimidin]-4-yl]benzenesulfonamide; Ro 47-8634 ; |
| Solubility | Methanol, Sparingly Soluble in Chloroform, Dichloromethane |
| Storage condition | -20?C Freezer |
| References | Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998) |
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