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Cat. Number
733967958887262
Chemical Name
3-Amino-1,2,4-benzotriazine 1,4-Dioxide
CAS Number
27314-97-2
Category
Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C7H6N4O2
Mol. Weight
178.15
Qty 1
100mg
Qty 2
1g
Appearance
Orange to Red Solid
Application Notes
A bioreductive anticancer agent. Selectively toxic to cells under hypoxic conditions. An antineoplastic.
Synonym
1,2,4-Benzotriazin-3-amine 1,4-Dioxide; SR 259075; SR 4233; Tirapazamine; Tirazone; Win 59075;
Melting Pt.
220°C dec.
Solubility
DMSO, Methanol
Storage condition
-20?C Freezer
References
Brown, J.M.: Brit. J. Cancer, 67, 1163 (1993), Johnson, C.A., et al.: J. Clin. Oncol., 15, 773 (1997)
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