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The distribution of N-linked glycans plays a critical role in the efficacy, immunogenicity, and pharmacokinetics of therapeutic proteins. Multi-step, multi-day , sample preparation methods have limited N-linked glycan analysis to only samples that represent critical decision points. Glycan analysis for bioreactor control, strain selection or comparability studies has never been possible.
速度快:
From purification to glycan release and labeling, the entire sample prep can be completed in 3 hours, not 3–4 days.
requires minimal equipment: a centrifuge with a deep-well plate rotor (minimum 44 mm height), a Starter Labware Kit, and Heater and Incubation Blocks.
This is modular and can be integrated into any workflow, regardless of sample throughput or sample type. The GlykoPrep platform is a streamlined solution for anyone that requires rapid, quantitative glycan profiling on your current analysis platform.
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Analysis
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