上海惠诚生物专业提供 sphingolipids, glycosphingolipids, gangliosides, globotriaosylceramides, fatty acids, and sterols
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Gangliosides are acidic glycosphingolipids that contribute a substantial presence to the outer leaflet of the cell plasma membrane. This is especially apparent in neuronal cells of the central nervous system where they have vital roles as neurotransmitters and cellular regulators.1 They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis.2 Gangliosides have been implicated in numerous types of cancer where they are often over-expressed on the membrane surface.3 A deficiency in the enzymes responsible for metabolizing gangliosides allows them to accumulate to toxic levels in several lysosomal storage diseases including GM1 gangliosidosis, GM2 gangliosidosis, Tay-Sachs disease, and Sandhoff disease. Matreya now offers a number of high purity deuterated gangliosides which are ideal for mass spectrometry studies.4
References:
T. Kolter "Ganglioside Biochemistry" International Scholarly Research Network, Vol. 2012 pp. 1-36, 2012
S. Birkle, G. Zeng, L. Gao, R.K. Yu, and J. Aubry "Role of tumor-associated gangliosides in cancer progression" Biochimie, Vol. 85 pp. 455-463, 2003
P. Giussani et al., "Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance" International Journal of Molecular Sciences, Vol. 15 pp. 4356-4392, 2014
J. Gu, C. Tifft and S. Soldin "Simultaneous quantification of GM1 and GM2 gangliosides by isotope dilution tandem mass spectrometry" Clinical Biochemistry, Vol. 41(6) pp. 413-417, 2008
神经节苷脂产品名称
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| 产品名称 | CAS |
| Anti-ganglioside asialo GM2 (polyclonal antibody) |
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| N-omega-CD3-Octadecanoyl monosialoganglioside GM1 (NH4+salt) |
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| N-omega-CD3-Octadecanoyl monosialoganglioside GM2 (NH4+salt) |
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| N-omega-CD3-Octadecanoyl monosialoganglioside GM3 (NH4+salt) |
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| N-己酰基 - 生物素 - 单唾液酸神经节苷脂GM1 N-Hexanoyl-biotin-monosialoganglioside GM1 |
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| 双唾液酸神经节苷脂GD3 Disialoganglioside GD3 (NH4+salt) | 62010-37-1 |
| 单唾液酸神经节苷酯,GM4,(鸡蛋),(NH4+ salt) Monosialoganglioside, GM4, (egg), (NH4+ salt) | 66456-69-7 |
| 岩藻糖基化单唾液酸神经节苷脂GM1，(猪甲状腺)Fucosylated monosialoganglioside GM1, (porcine thyroid) | 71812-11-8 |
| 四唾液酸神经节苷脂GQ1b(NH4 +盐) Tetrasialoganglioside GQ1b (NH4+salt) | 68652-37-9 |
| 双唾液酸神经节苷脂GD3(NH4+salt) Disialoganglioside GD3 (NH4+salt) | 62010-37-1 |
| 单唾液酸神经节苷脂GM2,(NH4 +盐) Monosialoganglioside GM2, (NH4+ salt) | 19600-01-2 |
| 二唾液酸神经节苷脂GD1b(NH4 +盐) Disialoganglioside GD1b (NH4+salt) | 19553-76-5 |
| 混合神经节苷脂,纯化,(牛脑)Mixed Gangliosides,Purified, (bovine brain) |
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| 三唾液酸神经节苷脂GT1b(NH4 +盐) Trisialoganglioside GT1b (NH4+salt) | 59247-13-1 |
| 双唾液酸神经节苷脂GD1a(NH4 +盐) Disialoganglioside GD1a (NH4+salt) | 12707-58-3 |
| 单唾液酸神经节苷脂GM1(NH4 +盐) Monosialoganglioside GM1 (NH4+salt) | 37758-47-7 |
| Anti-ganglioside GD2 (polyclonal antibody to GD2, isotype IgG, IgM) |
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| N-Octadecanoyl-D3-monosialoganglioside GM1(NH4+salt);N-D3-Stearoyl GM1 |
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| 生物素标记单唾液神经节苷酯Biotin-C6:0-GM1,N-Hexanoyl-biotin-monosialoganglioside GM1 |
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| 单唾液神经节苷酯 Monosialoganglioside Mixture(GM3, GM2, GM1) |
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| 双唾液酸神经节苷酯混合物,Disialoganglioside Mixture |
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| 神经节苷脂GD3单克隆抗体 Anti-ganglioside GD3 (monoclonal antibody) |
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| 三唾液酸神经节甘酯GT1b,Trisialoganglioside GT1b (NH4+salt);GT1b | 59247-13-1 |
| 神经节苷脂GQ1b四钠盐,Tetrasialoganglioside GQ1b (NH4+salt);GQ1b | 68652-37-9 |
| N-omega-CD3-Octadecanoyl monosialoganglioside GM3 (NH4+salt) |
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| N-omega-CD3-Octadecanoyl monosialoganglioside GM2 (NH4+salt) |
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| Monosialoganglioside GM1(NH4+salt) | 37758-47-7 |
| N-omega-CD3-Octadecanoyl monosialoganglioside GM1 (NH4+ salt) |
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| 单唾液酸神经节苷酯GM3,Monosialoganglioside GM3 (NH4+ salt);GM3 | 54827-14-4 |
| 单唾液酸神经节苷酯GM4,Monosialoganglioside GM4, egg (NH4+salt);GM4 | 66456-69-7 |
| 单唾液酸神经节苷酯GM1 Monosialoganglioside GM1 (NH4+salt);GM1 | 37758-47-7 |
| 单唾液酸神经节苷酯GM2 Monosialoganglioside GM2 (NH4+salt);GM2 | 19600-01-2 |
| 混合神经节甘脂,Mixed Gangliosides, purified, porcine, (NH4+salt) |
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| 混合神经节甘脂 ,Mixed Gangliosides,purified, bovine (NH4+salt) |
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| 岩藻糖单唾液酸神经节苷酯 Fucosylated monosialoganglioside GM1;Fucosyl-GM1 | 71812-11-8 |
| 双唾液酸神经节苷脂GD3,Disialoganglioside GD3 (NH4+salt);GD3 | 62010-37-1 |
| 双唾液酸神经节苷脂GD2,Disialoganglioside GD2 (NH4+salt);GD2 | 65988-71-8 |
| 双唾液酸神经节苷脂GD1b,Disialoganglioside GD1b (NH4+salt);GD1b | 19553-76-5 |
| 双唾液酸神经节苷脂GD1a，Disialoganglioside GD1a (NH4+salt)；GD1a | 12707-58-3 |
| 溶菌酶-单唾液酸神经节苷酯 lyso-Monosialoganglioside GM1 (NH4+salt);lyso-GM1 | 171483-40-2 |
| 抗神经节苷脂GM4多克隆抗体 Anti-ganglioside GM4(polyclonal antibody) |
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| 神经节苷脂GM2多克隆抗体 Anti-ganglioside GM2 (NANA)(polyclonal antibody) |
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| Anti-ganglioside GD2 (polyclonal antibody to GD2, isotype IgG, IgM) |
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| 神经节苷脂GM1多克隆抗体 Anti-ganglioside GM1 (polyclonal antibody) |
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| Anti-ganglioside GD1b (polyclonal antibody to GD1b, isotype IgG, IgM) |
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| Anti-ganglioside asialo-GM2 (polyclonal antibody) |
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| Anti-ganglioside asialo GM1 (polyclonal antibody) |
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| GM3-Ganglioside labelled by NBD |
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| GD3-Ganglioside | 62010-37-1 |
| GT1b-Ganglioside | 59247-13-1 |
| GM1-Ganglioside | 37758-47-7 |
| GD1b-Ganglioside | 19553-76-5 |
| GD1a-Ganglioside | 12707-58-3 |
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